mesothelioma prognosis


What Is Mesothelioma? Mesothelioma caused by asbestos exposure may prove to be a public health crisis as more people are diagnosed with this rare form of cancer Mesothelioma, also called malignant mesothelioma, is a rare but deadly form of cancer that typically occurs in the membrane around the lungs, called the pleura

This type of cancer is usually the result of inhaling asbestos fibers over a long period of time Most people with mesothelioma, were exposed to asbestos at work, such as in a shipyard, an asbestos mine, an automotive plant, or at a construction site Mesothelioma: What Is It? The mesothelium is the generic term used to describe the lining that covers many organs and body cavities Mesothelial tissue helps to protect organs and minimize trauma during movement In addition to the pleura, other mesothelia include: The peritoneum, which covers the walls of the abdominal cavity The pericardium, which encases the heart The tunica vaginalis testis, which covers the male internal reproductive organs The tunica serosa uteri, which covers the female internal reproductive organs Mesothelioma can affect any of these mesothelial tissues, though the pleura is by far the most common site

Mesothelioma: The Asbestos Risk Factor When asbestos fibers are inhaled into the lungs, they tend to remain there, and with continuous long-term exposure, the fibers begin to collect at the bottom of the lungs, where they become trapped in the pleura Over time, this can lead to cancer, especially if there are other aggravating factors like a genetic predisposition or a history of smoking "Asbestos irritates the lining of the lung and causes inflammation, and then the inflammatory response and the secondary changes in the lungs and pleural space may eventually lead to a malignant degeneration," explains Timothy Winton, MD, associate professor of surgery and division director of thoracic surgery at the University of Alberta Hospital in Edmonton, Canada One of the most striking things about mesothelioma is how long it takes for the disease to develop: Up to five decades may elapse from initial asbestos exposure to the development of cancer But when mesothelioma finally develops, it often becomes very aggressive and can spread beyond the pleura to other mesothelial tissues

The average survival time for malignant mesothelioma ranges between four and 18 months, and about 10 percent of patient live at least five years after being diagnosed In rare cases of slow-growing mesothelioma, survival can extend to 20 years Risk Factors for Mesothelioma Mesothelioma is a rare but deadly cancer that affects the linings of various organs Asbestos exposure is the No 1 risk factor for mesothelioma, but other risk factors also have been identified

Mesothelioma is a deadly cancer that affects the mesothelium The mesothelium is the membrane, like a net, that covers many organs in the body, such as the lungs and the heart It has two layers: One covers the organ, the other acts like a sac, letting the organ move, if necessary People who develop mesothelioma have usually been exposed to a substance that infiltrated the mesothelium Mesothelioma Risk Factors: Long-Term Asbestos Exposure Among the risk factors for mesothelioma, exposure to asbestos dust is by far the most important

About 70 percent to 80 percent of mesothelioma patients report a history of asbestos exposure at work And because asbestos was widely used in industry, car manufacturing, and construction until just a few decades ago, millions of US workers had long-term exposure to asbestos and still are at risk for the disease Leading the list are: Asbestos miners Shipyard workers Makers of asbestos products and textiles Workers in the heating and construction industries Mesothelioma Risk Factors: Short-Term Asbestos Exposure Many more people with shorter or less intensive exposure to asbestos face reduced but still real risks

For instance, demolition workers, firefighters, drywall removers, asbestos removal workers, and automobile workers may also be exposed to asbestos fibers Even family members of asbestos workers may be exposed to asbestos dust because the workers bring it home on their clothing One particular group that may be at elevated risk are the crews involved in the cleanup of the World Trade Center in New York City after 9/11 Asbestos was used in the construction of the North Tower and it is estimated that hundreds of tons of asbestos were among the debris The risks posed by asbestos exposure can be hard to quantify, but in general risk depends on: The quantity of asbestos the person was exposed to The length of time the person was exposed The size, shape, and chemistry of the asbestos fibers Personal risk factors, such as smoking There are two main forms of asbestos, amphibole (straight fibers) and chrysotile (curly fibers)

Although all asbestos is dangerous, recent studies suggest that exposure to amphibole asbestos may pose a greater risk of mesothelioma than chrysotile asbestos because amphibole fibers remain in the lungs longer Mesothelioma: A Public Health Issue Mesothelioma is a rare disease � only 2,000 to 3,000 new cases are diagnosed each year in the United States However, in other countries, the incidence of mesothelioma continues to increase "Because of the history of the use of asbestos and the known long latency between exposure and development of disease, the incidence of this type of disease around the world is going to continue to go up through the next two to three decades," Dr Winton says

"There are a lot of workers around the world who were exposed in an industrial setting and who need to be carefully followed" If you think you have been exposed to asbestos, let your doctor know and make sure you get regular checkups As with most cancers, early diagnosis is important to treating this disease Mesothelioma Risk Factors: While it is clear that the risks climb with more intensive exposure over longer periods of time, some people have gotten mesothelioma after only brief exposure to asbestos, while others who were intensively exposed do not "There is a lot of work being done to try to find links to genetic predisposition to the disease," says Timothy Winton, MD, an associate professor of surgery, and division director of thoracic surgery, of the University of Alberta in Edmonton, Canada

"There is also often a co-morbid history of smoking or a genetic predisposition to smoking-related problems With many cancers � and mesothelioma is one of them � you may need multiple hits from different carcinogens before you develop the disease" Mesothelioma Risk Factors: Simian Virus 40 (SV40) In the 1950s some polio vaccines were contaminated with SV40, which has been shown to cause mesothelioma in laboratory animals In humans, an association between SV40 and mesothelioma has been suggested because SV40 has been found in human mesothelioma tumors, but no clear connection has been established Mesothelioma Risk Factors: Thorium Dioxide and X-Ray Imaging Some studies have linked the use of the X-ray radioactive contrast medium thorium dioxide (Thorotrast) to an increased incidence of cancer, including mesothelioma

One study found that a group exposed to thorium dioxide had a cumulative incidence of peritoneal mesothelioma (the peritoneum lines the stomach cavity) as much as 06 percent higher than asbestos-exposed workers Thorium dioxide has not been used in X-ray imaging for many years Mesothelioma Risk Factors: Zeolites Zeolites are minerals found naturally in volcanic rock and ash that contain hydrated aluminum and silicon In synthetic forms, zeolites are used in detergents, for water and air purifications, and in other uses

Exposure to airborne zeolite dust has been associated with high incidence of mesothelioma in Turkey In one Turkish village, a form of zeolite used to whitewash houses caused pleural mesothelioma incidence to soar to 4409 per 100,000 for women and 2981 per 100,000 for men links are very important What are symptoms of Mesothelioma ? https://www

youtubecom/watch?v=7KVxBOuNkhU&index=1&list=PLlNrV2P827eM0zAd7iTtOa6MF7L26qctU&t=406s Mesothelioma Prognosis https://wwwmesotheliomacom/mesothelioma/prognosis/

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